Ginseng

CLINICAL STUDIES ON THE FOLLOWING INGREDIENTS:

AN INSIGHT INTO THE RESEARCH CONCERNING PANAX GINSENG C. A. MEYER POLYSACCHARIDES: A REVIEW

Ginseng polysaccharides are major bioactive components with antitumor, immunoregulatory, antioxidant, hepatoprotective, and anti-inflammatory effects. This review details extraction, purification, characterization, and bioactivity, highlighting that uronic acid-rich polysaccharides and specific glycosidic linkages are crucial for anti-inflammatory and antiviral actions. The work provides a comprehensive bibliography to support further innovation and application of ginseng polysaccharides in functional foods.

Source: https://www.tandfonline.com/doi/full/10.1080/87559129.2020.1771363

RECENT TRENDS IN GINSENG RESEARCH

A review of 1,208 studies on Panax ginseng reveals major research areas: pharmacology, chemical components, molecular biology, cultivation, tissue culture, and clinical trials. Most research focuses on ginsenosides, exploring their pharmacological mechanisms, genetic diversity, biosynthesis, and the influence of cultivation conditions. The paper highlights the growing interest in understanding ginseng’s bioactive compounds and their health effects.

Source: https://pubmed.ncbi.nlm.nih.gov/38512649/

ADVANCES AND CHALLENGES IN GINSENG RESEARCH FROM 2011 TO 2020: THE PHYTOCHEMISTRY, QUALITY CONTROL, METABOLISM, AND BIOSYNTHESIS

This review covers progress in ginseng research, including discovery of new compounds (notably saponins and polysaccharides), quality control, metabolism, and biosynthesis. Advances in analytical technologies have improved systematic analysis and global consumption. The paper discusses challenges and future trends, emphasizing the need for precise quality control and understanding of ginseng’s complex chemistry.

Source: https://pubs.rsc.org/en/content/articlelanding/2022/np/d1np00071c

PHARMACOLOGICAL POTENTIAL OF GINSENG AND ITS MAJOR COMPONENT GINSENOSIDES

Ginseng contains active ingredients like ginsenosides, which have antioxidative, anticancer, immunomodulatory, energy-boosting, and cardioprotective effects. Research supports benefits for diabetes, neurological diseases, and cardiovascular health. Ginseng is generally safe but may interact with drugs; higher-quality evidence is needed for clinical recommendations.

Source: https://pubmed.ncbi.nlm.nih.gov/33841000/

BEYOND GENOME: ADVANCED OMICS PROGRESS OF PANAX GINSENG

This review summarizes advances in ginseng genomics, transcriptomics, and proteomics, which have enabled the discovery of genes related to ginsenoside biosynthesis and stress resistance. Omics studies help understand gene expression, protein function, and secondary metabolite regulation, providing a foundation for future systems biology research and ginseng improvement.

Source: https://www.researchgate.net/publication/377957735_Beyond_Genome_Advanced_Omics_Progress_of_Panax_Ginseng

IMMUNOMODULATORY, ANTI-INFLAMMATORY, AND ANTI-CANCER PROPERTIES OF GINSENG: A PHARMACOLOGICAL UPDATE

Ginseng and its compounds (ginsenosides, polysaccharides) exhibit immunomodulatory, anti-inflammatory, and anti-cancer effects. The review covers studies on isolated compounds and extracts from various plant parts, highlighting their potential in modulating immune responses and inhibiting cancer progression.

Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC10180039/

REVIEW ON GINSENG AND ITS POTENTIAL ACTIVE SUBSTANCE G-RG2 AGAINST AGE-RELATED DISEASES: TRADITIONAL EFFICACY AND MECHANISM

Ginseng, especially its active component G-Rg2, is traditionally used for anti-aging and treating age-related diseases. G-Rg2 shows anti-apoptotic, anti-inflammatory, and antioxidant effects, particularly benefiting cardiovascular and neurodegenerative conditions. Network pharmacology and molecular docking support its therapeutic potential.

Source: https://pubmed.ncbi.nlm.nih.gov/39260708/

ROLES AND MECHANISMS OF GINSENOSIDE IN CARDIOVASCULAR DISEASES: PROGRESS AND PERSPECTIVES

Ginsenosides, the main active ingredients in ginseng, have protective effects against atherosclerosis, arrhythmia, myocardial ischemia, and ventricular remodeling. The review details pharmacological actions and mechanisms, supporting expanded clinical applications for cardiovascular diseases.

Source: https://link.springer.com/article/10.1007/s11427-016-5007-8

RECENT ADVANCES ON GINSENG RESEARCH IN CHINA

This review summarizes over 300 studies on ginseng’s chemical constituents, pharmacological actions, and clinical applications. Ginsenosides content varies by plant part and age. Ginseng acts on the central nervous, cardiovascular, and endocrine systems, promotes immunity, and has anti-stress and anti-aging effects. Many ginseng preparations are approved for clinical use in China.

Source: https://pubmed.ncbi.nlm.nih.gov/1501490/

STATE OF PANAX GINSENG RESEARCH: A GLOBAL ANALYSIS

A bibliometric analysis of 3,974 papers (1959–2016) shows global growth in ginseng research, led by South Korea and China. Main research areas are pharmacology, plant science, and integrative medicine. The field is shifting from basic science to multidisciplinary applications.

Source: https://pubmed.ncbi.nlm.nih.gov/28892002/